Panini Three and Two is the newest of Panini's baseball lines and the odd one out in format: a five-card box in which the autograph and the memorabilia card arrive already encapsulated in Panini-branded slabs, with three base cards, inserts or parallels alongside them. It launched in October 2022 at a high-end price and has released annually since, with a 2026 edition scheduled for September 2026. As with every Panini baseball release there is no MLB license, so the players are shown without team logos; the pitch is on-card autographs of prospects and stars, the Downtown insert borrowed from Panini football, and the novelty of pulling a slabbed card from a pack. This page covers the box, prices for every year and whether it is worth buying sealed.
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| Brand | Panini America |
| First year | 2022 |
| Release window | Fall of the following year in the early editions (2024 edition released February 2025); 2025 edition October 2025; 2026 edition scheduled September 2026 |
| License | MLBPA players license only; no MLB team logos or marks |
| Box formats | Hobby box, First Off the Line box, hobby case |
| Guaranteed hits | 1 slabbed autograph and 1 slabbed memorabilia card per 5-card box |
| Hobby box (live) | $623–$630hobby box · 2025 · 2 live listings |
A Three and Two hobby box is a single pack of five cards: one autograph and one memorabilia card, each sealed in a Panini slab, plus three base cards, inserts or parallels. Distributor pricing has moved around: the 2024 edition listed near $700 at release and was discounted to about $550, the 2025 edition listed at $600, and the 2026 edition is on presale at $400. On the secondary market, 2025 boxes have sold between $230 and $650 since release, with most sales at $370-$500 as of August 2026, and 2024 boxes at $350-$550. The 2026 presale price is the lowest launch price in the line's history.
Panini has sold FOTL versions with exclusive parallels for the recent editions. FOTL boxes sell for $100-$250 above the standard box and are the version that accounts for most of the highest secondary-market sales in each year's data. Given how much the standard box price swings, FOTL is the sensible choice only if you want the exclusive parallels for a set.
Cases are small, and the case count has changed year to year, so confirm the box count with the seller before pricing. Because each box is two hits, a case is the practical way to chase the Downtown and Blank Slate inserts and the triple-autograph cards, which are seeded well below one per box. Cases trade close to the sum of their boxes with no meaningful discount.
| Year | Hobby box (Aug 2026) | FOTL | Key rookies / chase |
|---|---|---|---|
| 2026 | $400 presale (Sept 2026 release) | TBA | Bobby Witt Jr. and Paul Skenes autograph roster, Timeless Moments Signatures, Downtown and Blank Slate inserts |
| 2025 | $370-$500 | $500-$650 | Ethan Holliday, Vance Honeycutt, Aaron Judge triple autographs, Spotlight Spikes Signatures |
| 2024 | $350-$550 | $600-$700 | Paul Skenes, Jackson Holliday, Wyatt Langford; first Downtown and Blank Slate inserts |
| 2023 | $200-$380 | $400-$500 | Elly De La Cruz, Gunnar Henderson, Corbin Carroll, Anthony Volpe |
| 2022 | $300-$500 | $500-$800 | Bobby Witt Jr., Julio Rodriguez, Adley Rutschman; Tatis and Ohtani inserts |
The 2023 box is the value outlier: it holds the same Elly De La Cruz and Gunnar Henderson rookie autographs that drive the 2023 National Treasures box, yet it sells for a third of the price, and it has been rising from a low near $150 in 2023 to the high $300s in 2026. The 2022 box has the advantage of being the first edition with Witt Jr. and Rodriguez, and its price has held better than the 2024 and 2025 boxes, which launched high and have drifted down as distributors discounted. The 2026 edition, with its lower launch price, is the first year where the box price looks in line with two hits.
The autograph in every box is on-card, and the checklist runs from prospects and rookies through veterans like Judge and Witt to legends, with Jersey Autographs, Spotlight Spikes Signatures and Timeless Moments Signatures as the named subsets and triple-autograph cards as the top of the ladder. Memorabilia comes as Full Count Swatches, Franchise Futures Memorabilia and Baseball's Best Memorabilia, all using Panini-sourced or event material rather than MLB game-used pieces. Both hits are slabbed with a Panini label that identifies the card and parallel.
The 2024 edition introduced Downtown and Blank Slate, the two case-hit inserts that give the line its non-autograph chase, and both continued in 2025 and 2026. With only three non-hit cards per box, a Downtown is a serious pull, and Panini has not published odds beyond calling them ultra-rare. Base parallels include numbered versions down to 1/1, and because there are so few base cards per box the numbered parallels are a real share of the three filler slots rather than a rare bonus.
Three and Two is a two-hit box priced like a four-hit box, and the slabs do not add value to the cards inside; a Panini-slabbed autograph sells for the same as a raw one and often gets cracked out for grading. That makes the average box a poor expected-value rip at $500-$700 launch prices, which is why the 2024 and 2025 boxes lost value after release. The 2026 edition at $400 changes the math somewhat but does not make it a value product. The sealed-hold case is strongest for 2023, where the rookie class and the rising price line are both in the buyer's favor, and for 2022 as the first edition. The line is active as of 2026, which means new supply each year and no scarcity premium yet for any edition.
Three and Two boxes are rigid boxes sized to hold two slabs, with clear shrink and a Panini hologram seal; the contents are a single sealed pack containing the slabs and the loose cards. The slabs themselves are what to inspect on any opened card: a Panini slab has a printed label with the card details and a sonically sealed case, and cracked-and-reglued slabs show a seam or a label that has been reinserted. For sealed boxes, check that the shrink is heat-sealed rather than cut and glued and that the hologram is intact. Because the box is one pack, pack searching is not a concern, but "box with slabs removed" listings are opened product and should be priced as three loose cards. FOTL boxes carry an FOTL sticker; ask for the Panini order confirmation.
Shops with a Panini account can order Three and Two for the fall release, and many discount 2024 and 2025 boxes below distributor cost, so check the card shop directory and ask for current pricing rather than the printed price. Card shows are the place to find 2022 and 2023 boxes, which have mostly left distributor inventory. On eBay these searches keep the results to sealed boxes:
No. Panini has no MLB license, so Three and Two cards have no team logos or team names. Player rights came through Panini's MLBPA license, which ran through 2025, and Panini has continued releasing unlicensed baseball products in 2026, including a 2026 Three and Two edition.
One pack of five cards: one slabbed autograph, one slabbed memorabilia card and three base cards, inserts or parallels.
As of August 2026, sealed 2025 boxes sell for $370-$500, 2024 boxes for $350-$550 and 2023 boxes for $200-$380. The 2026 edition is on presale at about $400.
Yes. The line has released every year since 2022, and the 2026 edition is scheduled for September 2026.
The 2023 box, which holds Elly De La Cruz and Gunnar Henderson rookie autographs at a fraction of the National Treasures price, followed by the 2022 first edition.
No. The Panini slab is an authentication and presentation case, not a grade. Many collectors crack the slabs to submit the cards to PSA or BGS.
Prices in this guide were last reviewed 2026-08. Live eBay listings above update daily.